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Table 4 Detectable autoantibodies in AIH-1, AIH-2 and AIH as part of APECED

From: Autoantibodies and autoantigens in autoimmune hepatitis: important tools in clinical practice and to study pathogenesis of the disease

AIH-1 or AIH-2

AIH in APECED

ANA, SMA, ANCA, anti-ASGP-R anti-SLA/LP (molecular target: UGA suppressor tRNA-associated protein), anti-LKM-1 (molecular target: CYP2D6), anti-LKM-3 (molecular target: UGT1), anti-LC1 (molecular target: FTCD)

ANA, anti-LC (molecular target: unknown), anti-LKM (molecular targets: CYP2A6, CYP1A1 and CYP2B6), anti-LM (specific autoantibody; molecular target: CYP1A2)

  1. Abbreviations are the same as shown in the text.
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Journal of Autoimmune Diseases

ISSN: 1740-2557