Table 5 Differential diagnosis of chronic liver diseases according to the presence or absence of autoantibodies against molecularly defined autoantigens of cytochrome P450 complex using the radioligand assay.
Anti-CYP2D6 | Anti-CYP2A6 | Anti-CYP1A2 | Chronic liver disease |
|---|---|---|---|
+ | - | - | AIH-2 (94–100%), HCV (0–10%) |
- | + | - | HCV, APECED with or without hepatitis |
- | - | + | AIH in APECED, drug induced hepatitis |
+ | + | - | HCV (0–7%) |
- | + | + | AIH in APECED |