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Table 2 sCTLA-4 levels in AbN, T1D and AbP individuals. Values presented are mean and 95% confidence interval in ng/ml.

From: Lack of correlation between the levels of soluble cytotoxic T-lymphocyte associated antigen-4 (CTLA-4) and the CT-60 genotypes

Group AbN AbP T1D T1D/AbN AbP/AbN
All subjects (p = 0.58) 1.7 (0.6–3.6) (n = 117) 2.2 (0.5–5.5) (n = 19) 2.2 (0.9–4.6) (n = 82) 1.3 1.3
CTLA-4 genotype      
A/A 1.9 (0.7–4.1) (n = 12) 2.5 (n = 1) 1.9 (0.8–4.9) (n = 19) 1.0 1.2
A/G 1.5 (0.5–4.0) (n = 21) 1.7 (0.4–4.2) (n = 7) 1.9 (0.7–3.8) (n = 16) 1.2 1.1
G/G 1.6 (0.7–3.0) (n = 49) 2.5 (0.9–5.4) (n = 9) 2.4 (1.1–4.4) (n = 26) 1.3 1.3
Male (p = 0.53) 1.7 (0.9–2.8) (n = 53) 2.3 (0.9–4.5) (n = 9) 2.3 (1.3–3.7) (n = 51) 1.4 1.3
Female (p = 0.70) 1.7 (0.9–2.8) (n = 64) 2.1 (0.8–4.2) (n = 10) 2.2 (1.2–3.6) (n = 31) 1.3 1.2
DQB1*0201 positive 1.3 (0.6–2.4) (n = 60) 1.8 (0.6–4.0) (n = 8) 2.2 (1.1–3.8) (n = 62) 1.7 1.4
DQB1*0201 negative 2.2 (1.2–3.8) (n = 53) 3.3 (1.4–6.8) (n = 10) 1.9 (0.8–3.8) (n = 19) 0.9 1.5
DQB1*0302 positive 1.6 (0.8–2.9) (n = 66) 2.4 (1.0–4.6) (n = 13) 2.3 (1.2–3.9) (n = 56) 1.4 1.5
DQB1*0302 negative 1.9 (0.9–3.3) (n = 47) 2.6 (0.9–5.9) (n = 5) 1.8 (0.7–3.6) (n = 25) 1.0 1.4