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Table 1 Selected studies exploring the relation of multiple sclerosis with human herpes virus-6

From: Virus-mediated autoimmunity in Multiple Sclerosis

Material used Method followed Relation to MS Year of publication
Brain tissue Viral DNA-PCR, immunohistochemistry Positive 1995[44]
  Viral DNA-PCR Negative 1996[49]
  Viral DNA-PCR, immunohistochemistry Positive 1999[47]
  Immunohistochemistry Positive 2000[58]
  Viral DNA-PCR Positive 2000[59]
  Viral DNA-PCR, immunohistochemistry Positive 2003[60]
  Viral DNA-PCR Uncertain 2003[48]
CSF Viral DNA-PCR Negative 1999[50]
  Viral DNA-PCR, antibodies titer Negative 2000[51]
  Viral DNA-PCR, antibodies titer Positive 2002[52]
Serum Viral DNA-PCR Negative 1999[50]
  Viral DNA-PCR, antibodies titer Positive 2000[52]
  Viral DNA-PCR Positive 2000[53]
  Viral DNA-PCR Positive 2001[54]
  Viral DNA-PCR Negative 2002[55]
  Viral DNA-PCR, antibodies titer Positive 2003[56]
Peripheral blood mononuclear cells Viral DNA-PCR Negative 2000[51]
  Viral DNA-PCR Positive 2000[53]
  Viral DNA-PCR Negative 2000[57]
  Viral DNA-PCR Positive 2001[54]
  Viral DNA-PCR Positive 2002[55]
  Viral DNA-PCR Positive 2003[56]