Virus-mediated autoimmunity in Multiple Sclerosis

Table 1 Selected studies exploring the relation of multiple sclerosis with human herpes virus-6

Material used	Method followed	Relation to MS	Year of publication
Brain tissue	Viral DNA-PCR, immunohistochemistry	Positive	1995[44]
	Viral DNA-PCR	Negative	1996[49]
	Viral DNA-PCR, immunohistochemistry	Positive	1999[47]
	Immunohistochemistry	Positive	2000[58]
	Viral DNA-PCR	Positive	2000[59]
	Viral DNA-PCR, immunohistochemistry	Positive	2003[60]
	Viral DNA-PCR	Uncertain	2003[48]
CSF	Viral DNA-PCR	Negative	1999[50]
	Viral DNA-PCR, antibodies titer	Negative	2000[51]
	Viral DNA-PCR, antibodies titer	Positive	2002[52]
Serum	Viral DNA-PCR	Negative	1999[50]
	Viral DNA-PCR, antibodies titer	Positive	2000[52]
	Viral DNA-PCR	Positive	2000[53]
	Viral DNA-PCR	Positive	2001[54]
	Viral DNA-PCR	Negative	2002[55]
	Viral DNA-PCR, antibodies titer	Positive	2003[56]
Peripheral blood mononuclear cells	Viral DNA-PCR	Negative	2000[51]
	Viral DNA-PCR	Positive	2000[53]
	Viral DNA-PCR	Negative	2000[57]
	Viral DNA-PCR	Positive	2001[54]
	Viral DNA-PCR	Positive	2002[55]
	Viral DNA-PCR	Positive	2003[56]