Figure 4
From: Endothelial cell activation and neovascularization are prominent in dermatomyositis
DC-LAMP positive dendritic cells are enriched in perivascular area of inflammation in juvenile DM patients. Juvenile DM and control biopsies were stained with antibodies that recognize dendritic cell marker DC-LAMP along with an isotype matched control (upper panels). Consecutive sections stained with DC-LAMP and CD146 showing close proximity of DC-LAMP positive cells to blood vessels. Normal biopsies showed no staining with DC-LAMP antibodies (data not shown).