Journal of Autoimmune Diseases

Table 1 Improvement of psoriasis cutaneous expression after therapyand MMPs or cytokine levels released in tissue culture supernantans

From: Decreased levels of metalloproteinase-9 and angiogenic factors in skin lesions of patients with psoriatic arthritis after therapy with anti-TNF-α

	Baseline values	After 6 weeks	Paired t P
PASI score	19.1 ± 7.8	7.4 ± 2.7	0.0002
*TNF-α (pg/ml) 0.12	294.7 ± 123.5	194.9 ± 67.8	0.02
*MMP-9 (ng/ml) 0.15	207.3 ± 240.6	43.3 ± 73.9	0.03
*MMP-2 (ng/ml) 0.16	1404.0 ± 1081.0	1205.0 ± 1142.0	0.048
*VEGF (pg/ml) 9.0	510.7 ± 376.6	240.6 ± 270.1	0.02
*E-Selectin (ng/ml) 0.1	18.9 ± 23.5	4.1 ± 3.3	0.05

*Data are normalized per mg of tissue – **minimum detectable dose according to the manufacturer

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