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Figure 2 | Journal of Autoimmune Diseases

Figure 2

From: Autoantibodies against the chromosomal passenger protein INCENP found in a patient with Graham Little-Piccardi-Lassueur syndrome

Figure 2

Graham Little human autoantibody recognizes chromosomal passenger proteins in different mammalian cell lines. Staining of cells in anaphase (a, c, e, g) and midbody in cytokinesis (b, d, f, h) is shown for hamster (CHO in a-b), mouse (3T3 in c-d), bovine (MDBK in e-f) and monkey cells (CV-1 in g-h). The autoimmune serum reacts with conserved epitopes of passenger proteins in diverse species. Nuclei staining by Hoechst is shown in a'-h'.

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