Table 1 Patients' characteristics.
Parameters | Patients with liver diseases* (n = 423) | Patients with coincidence of AIH and any kind of liver disorder (n = 24)** | Patients with AIH/overlap syndromes (n = 10) | Patients with coincidence of AIH and other liver disease (n = 14) | Patients with AIH (n = 43) |
|---|---|---|---|---|---|
Gender (F/M) | 231/192 | 12/12 | 5/5 | 7/7 | 33/10 |
Age mean ± SD (years) | 51.6 ± 22.7 | 54.9 ± 18.6 | 49.6 ± 21.6 | 57.7 ± 15.5 | 52.3 ± 15.7 |
Serum globulin or IgG above normal (pos/neg; pos = score ≥ 1) | 202/221 | 17/7 | 7/3 | 10/4 | 34/9 |
Alcohol abuse (>60 g/day: yes/no) | 98/325 | 3/21 | 0/10 | 3/11 | 1/42 |
Drug use (yes/no) | 25/398 | 0/24 | 0/10 | 0/14 | 1/42 |
Other autoimmune diseases (yes/no) | 24/399 | 7/17 | 5/5 | 2/12 | 18/25 |
ANA or SMA or anti-LKM (pos/neg) (positive titre ≥ 1:40) | 335/88 | 23/1 | 9/1 | 14/0 | 43/0 |
AMA (pos/neg) | 49/374 | 4/20 | 4/6 | 0/14 | 0/43 |
Histology (pos/neg) (pos = score > 0, neg = score ≤ 0) | 58/365 | 13/11 | 3/7 | 10/4 | 35/8 |
   Total histologic score ± SD | -4 ± 3.3 | 0.38 ± 3.72 | -2.1 ± 4.4 | 2.14 ± 1.7 | 2.73 ± 1.98 |
   Median (range) | -5 (-11 to +5) | 1 (-8 to +4) | 0 (-8 to +4) | 3 (0 to +4) | 3 (-3 to +5) |