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Table 3 Comparisons of the parameters of the IAHG scoring system between patients with chronic liver diseases* achieving a probable (n = 8) and a negative AIH score (n = 415).

From: The revised international autoimmune hepatitis score in chronic liver diseases including autoimmune hepatitis/overlap syndromes and autoimmune hepatitis with concurrent other liver disorders

Characteristics Negative score no. of patients (%) Probable score no. of patients (%) P-value
Gender    
   Female 225 (54.2) 6 (75) NS
   Male 190 (45.8) 2 (25)  
ALP/ALT ratio    
   Positive: score +2 330 (79.5) 8(100) NS
   Negative: score 0, -2 85 (20.5) 0  
Serum globulin or IgG above normal    
   Positive (score ≥ 1) 196 (47.2) 6 (75) NS
   Negative (score 0) 505 (57.9) 2 (25)  
ANA, SMA or anti-LKM    
   Positive (titre ≥ 1:40) 327 (78.8) 8 (100) NS
   Negative 88 (21.2) 0  
AMA    
   Positive (titre ≥ 1:40) 48 (11.6) 1 (12.5) NS
   Negative 367 (88.4) 7 (87.5)  
Hepatitis viral markers    
   Yes 214 (51.6) 2 (25) NS
   No 201 (48.4) 6 (75)  
History of illicit drug use    
   Yes 25 (6) 0 NS
   No 390 (94) 8 (100)  
Average alcohol intake    
   <25 g/day 318 (76.6) 7 (87.5) NS
   >60 g/day 97 (23.4) 1 (12.5)  
Histological score    
   Positive (score > 0) 54 (13) 4 (50) 0.015**
   Negative (score ≤ 0) 361 (87) 4 (50)  
Aggregate histological score (mean ± SD) -4.13 ± 3.3 0.88 ± 2.8 <0.001***
Other autoimmune disease    
   Yes 23 (5.5) 1 (12.5) NS
   No 392 (94.5) 7 (87.5)  
Aggregate AIH score (mean ± SD) 2.29 ± 4.07 11.63 ± 1.19 <0.001***
  1. Abbreviations are same as in text; NS: not statistically significant; SD: standard deviation; *Excluding AIH patients (n = 43) and patients with coincidence of AIH and any kind of liver disorder (n = 24); **Fisher's exact test; ***Mann-Whitney U test;