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Table 4 Comparisons of the parameters of the IAHG scoring system between patients with chronic liver diseases* (n = 423) and patients with coincidence of AIH and any kind of liver disorder (n = 24).

From: The revised international autoimmune hepatitis score in chronic liver diseases including autoimmune hepatitis/overlap syndromes and autoimmune hepatitis with concurrent other liver disorders

Characteristics Patients with liver diseases* no. of patients (%) Patients with coincidence of AIH and any kind of liver disorder no. of patients (%) P-value
Gender    
   Female 231 (54.6) 12 (50) NS
   Male 192 (45.5) 12 (50)  
ALP/ALT ratio    
   Positive: score +2 338 (79.9) 20 (83.3) NS
   Negative: score 0, -2 85 (20.1) 4 (16.7)  
Serum globulin or IgG above normal    
   Positive (score ≥ 1) 202 (47.8) 17 (70.8) 0.035**
   Negative (score 0) 221 (52.2) 7 (29.2)  
ANA, SMA or anti-LKM    
   Positive (titre ≥ 1:40) 335 (79.2) 23 (95.8) 0.06***
   Negative 88 (20.8) 1 (4.2)  
AMA    
   Positive (titre ≥ 1:40) 49 (11.6) 4 (16.7) NS
   Negative 374 (88.4) 20 (83.3)  
Hepatitis viral markers    
   Yes 216 (51.1) 8 (33.3) NS
   No 207 (48.9) 16 (66.7)  
History of illicit drug use    
   Yes 25 (5.9) 0 NS
   No 398 (94.1) 24 (100)  
Average alcohol intake    
   <25 g/day 325 (76.8) 21 (87.5) NS
   >60 g/day 98 (23.2) 3 (12.5)  
Histological score    
   Positive (score > 0) 58 (13.7) 13 (54.2) <0.001**
   Negative (score ≤ 0) 365 (86.3) 11 (45.8)  
Aggregate histological score (mean ± SD) -4 ± 3.3 0.38 ± 3.72 <0.001****
Other autoimmune disease    
   Yes 24 (5.7) 7 (29.2) 0.001**
   No 399 (94.3) 17 (70.8)  
Aggregate AIH score (mean ± SD) 2.5 ± 4.2 10 ± 4.1 <0.001****
  1. Abbreviations are same as in text; NS: not statistically significant; SD: standard deviation; *Excluding AIH patients (n = 43) and patients with coincidence of AIH and any kind of liver disorder (n = 24); **Two by two x square after Yates' correction; ***Fisher's exact test; **** Mann-Whitney U test.