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Table 5 Comparisons of the parameters of the IAHG scoring system among patients with chronic liver diseases* (n = 423), AIH/overlap syndromes (n = 10) and patients with coincidence of AIH and other liver disease (n = 14).

From: The revised international autoimmune hepatitis score in chronic liver diseases including autoimmune hepatitis/overlap syndromes and autoimmune hepatitis with concurrent other liver disorders

Characteristics Patients with liver diseases* no. of patients (%) Patients with AIH/overlap syndromes no. of patients (%) Patients with coincidence of AIH and other liver disease no. of patients (%) P value
Gender     
   Female 231 (54.6) 5 (50) 7 (50) NS
   Male 192 (45.4) 5 (50) 7 (50)  
ALP/ALT ratio     
   Positive: score +2 338 (79.9) 8 (80) 12 (85.7) NS
   Negative: score 0, -2 85 (20.1) 2 (20) 2 (14.3)  
Serum globulin or IgG above normal     
   Positive (score ≥ 1) 202 (47.8) 7 (70) 10 (71.4) NS
   Negative (score 0) 221 (52.2) 3 (30) 4 (28.6)  
ANA, SMA or anti-LKM     
   Positive (titre ≥ 1:40) 335 (79.2) 9 (90) 14(100) NS
   Negative 88 (20.2) 1 (10) 0  
AMA     
   Positive (titre ≥ 1:40) 49 (11.6) 4 (40) 0 0.009**
   Negative 374 (88.4) 6 (60) 14(100)  
Hepatitis viral markers     
   Yes 216 (51.1) 0 8 (57.1) 0.005**
   No 207 (48.9) 10 (100) 6 (42.9)  
History of illicit drug use     
   Yes 25 (5.9) 0 0 NS
   No 398 (94.1) 10 (100) 14 (100)  
Average alcohol intake     
   <25 g/day 325 (76.8) 10 (100) 11 (78.6) 0.013**
   >60 g/day 98 (23.2) 0 3 (21.4)  
Histological score     
   Positive (score > 0) 58 (13.7) 3 (30) 10 (71.4) <0.001**
   Negative (score ≤ 0) 365 (86.3) 7 (70) 4 (28.6)  
Aggregate histological score (mean ± SD) -4± 3.3 -2.1± 4.4 2.14± 1.7 <0.001***
Other autoimmune disease     
   Yes 24 (5.7) 5 (50) 2 (14.3) <0.001**
   No 399 (94.3) 5 (50) 12 (85.7)  
Aggregate AIH score (mean ± SD) 2.5 ± 4.23 9.3 ± 4.8 10.5 ± 3.7 <0.001***
  1. Abbreviations are same as in text; NS: not statistically significant; SD: standard deviation; *Excluding AIH patients (n = 43) and patients with coincidence of AIH and any kind of liver disorder (n = 24); **Total x square (comparison amongst the three groups of patients; for statistical significance between groups see text of results; subheading Comparison between groups, second paragraph); ***Kruskal-Wallis test (comparison amongst the three groups of patients; for statistical significance between groups see text of results, subheading Comparison between groups, second paragraph).