From: Immunogenetic mechanisms for the coexistence of organ-specific and systemic autoimmune diseases
Disease | HLA allele | Autoantigen | Reference |
---|---|---|---|
Mixed Connective Tissue Disease | HLA-B7, HLA-Dw1 HLA-DQw3 | U1 sn-RNP polypeptide U1 sn-RNP polypeptide | 30 32 |
Mucous Membrane Pemphigoid | HLA-DQB1*0301 | β4 integrin | 19, 64 |
Bullous Pemphigoid | HLA-DQB1*0301 | BPAg1 (BP180) BPAg2 (BP230) | 18, 64 |
Pemphigus Vulgaris | HLA-DR4 (DRB1*0402), DQwB1*0302 HLA-DRB1*404, DQB1*0503 | Dsg3 Dsg3 | 65 65 |