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Table 1 HLA associations with Mixed Connective Tissue Disease and Autoimmune Blistering Diseases

From: Immunogenetic mechanisms for the coexistence of organ-specific and systemic autoimmune diseases

Disease HLA allele Autoantigen Reference
Mixed Connective Tissue Disease HLA-B7, HLA-Dw1
HLA-DQw3
U1 sn-RNP polypeptide
U1 sn-RNP polypeptide
30
32
Mucous Membrane Pemphigoid HLA-DQB1*0301 β4 integrin 19, 64
Bullous Pemphigoid HLA-DQB1*0301 BPAg1 (BP180)
BPAg2 (BP230)
18, 64
Pemphigus Vulgaris HLA-DR4 (DRB1*0402), DQwB1*0302
HLA-DRB1*404, DQB1*0503
Dsg3
Dsg3
65
65